The FIGO (International Federation of Gynecology and Obstetrics) staging system is used worldwide for staging carcinoma of the cervix. It is a clinical staging system that may be supported by imaging and pathological findings. It helps in determining prognosis, treatment planning, and comparison of treatment outcomes pre surgical disease..
Stage I: Carcinoma strictly confined to the cervix (extension to uterus is not considered)
- Stage IA: Invasive carcinoma diagnosed only by microscopy. Stromal invasion ≤5 mm in depth.
- IA1: Stromal invasion ≤3 mm in depth.
- IA2: Stromal invasion >3 mm and ≤5 mm in depth.
- Stage IB: Invasive carcinoma with stromal invasion >5 mm but limited to the cervix.
- IB1: Tumor ≤2 cm in greatest dimension.
- IB2: Tumor >2 cm and ≤4 cm.
- IB3: Tumor >4 cm.
Stage II: Carcinoma extends beyond the cervix but not to the pelvic wall or lower third of the vagina
- Stage IIA: Without parametrial invasion.
- IIA1: Tumor ≤4 cm.
- IIA2: Tumor >4 cm.
- Stage IIB: With obvious parametrial invasion but not up to the pelvic wall.
Stage III: Tumor involves the lower third of the vagina, pelvic wall, causes hydronephrosis or non-functioning kidney, or involves pelvic/para-aortic lymph nodes
- Stage IIIA: Involvement of the lower third of the vagina, but no extension to the pelvic wall.
- Stage IIIB: Extension to the pelvic wall and/or causing hydronephrosis or non-functioning kidney.
- Stage IIIC: Involvement of pelvic and/or para-aortic lymph nodes (regardless of tumor size or local extent)
- IIIC1: Pelvic lymph node involvement.
- IIIC2: Para-aortic lymph node involvement.
Note: Stage IIIC is a new addition introduced in the 2018 FIGO update, recognizing the importance of lymph node status in prognosis.
Stage IV: Carcinoma extends beyond the true pelvis or involves the mucosa of bladder or rectum
- Stage IVA: Spread to adjacent pelvic organs (e.g., bladder or rectal mucosa), confirmed via biopsy.
- Stage IVB: Distant metastasis (e.g., lungs, liver, bone).
Important Notes:
- Imaging (MRI, CT, PET-CT) and pathological findings are allowed to supplement clinical staging.
- Clinical examination remains the cornerstone of staging, especially in resource-limited settings.
- FIGO encourages precise tumor measurement and lymph node evaluation, enhancing accuracy in staging and treatment planning.
Conclusion: The FIGO staging system provides a structured and clinically useful way to classify cervical cancer. It emphasizes tumor size, local spread, lymph node involvement, and distant metastasis to guide appropriate treatment and predict outcomes.
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